Characterization of Chemical Exchange Using Residual Dipolar Coupling
نویسندگان
چکیده
منابع مشابه
Periodicity, planarity, residual dipolar coupling, and structures.
The periodic behavior of residual dipolar couplings (RDCs) arising from nucleic acid and protein secondary structures is shown to be more complex and information-rich than previously believed. We have developed a theoretical framework which allows the bond vector orientation of nucleic acids and the peptide plane orientations of protein secondary structures to be extracted from their Dipolar wa...
متن کاملH–C residual dipolar coupling on refinement
Ribonucleic acid structure determination by NMR spectroscopy relies primarily on local structural restraints provided by H–H NOEs and J-couplings. When employed loosely, these restraints are broadly compatible with Aand B-like helical geometries and give rise to calculated structures that are highly sensitive to the force fields employed during refinement. A survey of recently reported NMR stru...
متن کاملResidual Dipolar Coupling Constants: An Elementary Derivation of Key Equations
Residual dipolar couplings have recently found a wide range of applications in high-resolution NMR of biomolecules in the liquid state. A nonisotropic orientational distribution of a molecule of interest results in nonzero average dipolar coupling constants. Here, we present an intuitive introduction to the alignment tensor and an elementary derivation of key equations. © 2004 Wiley Periodicals...
متن کاملProtein Fold Recognition Through Application of Residual Dipolar Coupling Data
Residual dipolar coupling (RDC) represents one of the most exciting emerging NMR techniques for studying protein structures. However, solving a protein structure using RDC data alone is a highly challenging problem as it often requires that the starting structure model be close to the actual structure of a protein, for the structure calculation procedure to be effective. We report in this paper...
متن کاملUltrahigh resolution characterization of domain motions and correlations by multialignment and multireference residual dipolar coupling NMR.
Nuclear magnetic resonance (NMR) residual dipolar couplings (RDCs) provide a unique opportunity for spatially characterizing complex motions in biomolecules with time scale sensitivity extending up to milliseconds. Up to five motionally averaged Wigner rotation elements, (D(0k)2(alphaalpha)), can be determined experimentally using RDCs measured in five linearly independent alignment conditions ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 2007
ISSN: 0002-7863,1520-5126
DOI: 10.1021/ja0761636